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Treatment

Adrenal Cancer: Treatment Choices

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There are many treatment choices for adrenal cancer. Which may work best for you? It depends on things, such as:

  • The size of the tumor

  • Where the tumor is

  • Test results

  • The stage or extent of the disease

  • Your age

  • Your overall health

  • Your personal concerns and preferences

  • What side effects you’re willing to deal with


Learning about your treatment choices

You may have questions and concerns about your treatment choices. You may want to know how you’ll feel and function after treatment, and if you can do your normal activities.

Your healthcare provider is the best person to answer your questions. They can tell you what your treatment choices are and how well they’re expected to work. Your provider can also tell you what the risks and side effects are. Your provider may advise a certain treatment. Or more than 1 treatment may be suggested, and you decide which to use. It can be hard to make this decision. It's important to take the time you need to make the best decision.


Types of treatment

Adrenal cancer treatments may be local or systemic. Local treatments remove, destroy, or control cancer cells in 1 area. Surgery and radiation are local treatments.

Systemic treatments destroy or control cancer cells all over your body. Chemotherapy (chemo) is a systemic treatment.

You may have just 1 treatment. Or you may have a combination of treatments.


Goals of treatment

Different types of adrenal cancer treatments have different goals. The types of treatments and their goals include:

  • Surgery. The goal of surgery is to remove all of the tumor along with the whole adrenal gland. Sometimes nearby lymph nodes are also removed. 

  • Radiation therapy. Radiation therapy kills cancer cells using high energy X-rays. It might be used to treat any cancer cells left after surgery. Or it can be used to treat pain caused by tumor growth. It may also be used to treat cancer that can’t be taken out with surgery.

  • Chemotherapy. The goal of chemo is to kill cancer cells and shrink tumors. It might be used after surgery to reduce the chance that the cancer will come back. Chemo may also be used to treat cancer that has spread to other parts of the body.

  • Medicines to control hormone levels. These medicines help stop excess hormone production, lower the effects of some hormones, or replace hormones. They also ease symptoms caused by hormone imbalances. You may keep taking them after the main treatment is done.


Clinical trials for new treatments

Researchers are always looking for new ways to treat adrenal cancer. These new methods are tested in clinical trials. Before starting treatment, ask your healthcare provider if there are any clinical trials you should learn about.


Talking with your healthcare provider

At first, thinking about treatment choices may seem overwhelming. Talk with your healthcare providers, nurses, and loved ones. Make a list of questions. Learn about the benefits and possible side effects of each choice. Discuss your concerns with your provider before making a decision.

Deciding on the best plan may take some time. Talk with your healthcare provider about how much time you can take to explore your choices. You may want to get a second opinion before deciding on your treatment plan. You may also want to have your family and friends be part of this process.

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© 2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare provider's instructions.
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