Symptoms

Non-Hodgkin Lymphoma: Symptoms


What are the symptoms of non-Hodgkin lymphoma?

Non-Hodgkin lymphoma is a type of cancer that starts in your lymphatic (lymph) system. The lymph system is part of your immune system.

Non-Hodgkin lymphoma may not cause symptoms right away. Slow-growing lymphoma, also called indolent lymphoma, may not cause symptoms until it grows very large. Aggressive lymphoma grows and spreads quickly. It can cause bad symptoms.

When lymphoma does cause symptoms, they can often seem like other health problems at first. That's because non-Hodgkin lymphoma can cause many different kinds of symptoms. It depends on where it starts in your body and the kind of lymphoma it is.

Here are some common symptoms of non-Hodgkin lymphoma:

  • Swollen, often painless, lymph nodes in the neck, groin, underarm, or above the collarbone

  • Fever without an infection

  • Chills

  • Feeling very tired

  • Swelling in the belly (abdomen)

  • Feeling full after eating only a small amount

  • Upset stomach (nausea), vomiting, or stomach pain

  • Coughing, shortness of breath, or trouble breathing

  • Chest pain or pressure

  • Swelling in your head and arms (called superior vena cava syndrome)

  • Headaches

  • Trouble thinking or moving parts of your body

  • Itchy, red or purple lumps under the skin

  • Infections that come back

  • Abnormal sweating, especially at night

  • Losing weight without trying

  • Easy bleeding or bruising


When to contact your doctor

Many of these symptoms are more often caused by other health problems. Still, it’s important to see a health care provider if you have these symptoms. Only a provider can tell if you have cancer.

Featured in

© 2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare provider's instructions.
Related Articles
Read article
Immune Conditions
Acute Lymphocytic Leukemia (ALL): Status After Treatment

During and after treatment for acute lymphocytic leukemia, you will have many tests. These tests check your blood and bone marrow for leukemia cells. They are used to see how well treatment is working.

Read article
Immune Conditions
Chronic Lymphocytic Leukemia (CLL): Newly Diagnosed

Being told you have chronic lymphocytic leukemia (CLL) can be scary, and you may have many questions. But you have people on your health care team to help.

Read article
Immune Conditions
Hodgkin Lymphoma: Immunotherapy

Monoclonal antibody therapy is a type of treatment for cancer that is given in medicines to attack certain parts of cancer cells. Learn more about how this treatment works.

Read article
Hematology
Acute Myeloid Leukemia (AML): Treatment Choices

There are many treatment choices for acute myeloid leukemia. The best one for you depends on a number of factors.